Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.560 Biomarker disease RGD Deregulation of the p16-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway involved in the rat bladder carcinogenesis induced by terephthalic acid-calculi. 16896691 2006
Entrez Id: 5321
Gene Symbol: PLA2G4A
PLA2G4A
0.210 Biomarker disease RGD Elevated prostaglandin E2 level via cPLA2--COX-2--mPGES-1 pathway involved in bladder carcinogenesis induced by terephthalic acid-calculi in Wistar rats. 16621493 2006
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
0.210 ModifyingMutation disease RGD Overexpression of annexin a1 induced by terephthalic acid calculi in rat bladder cancer. 17994624 2007
Entrez Id: 335
Gene Symbol: APOA1
APOA1
0.200 Biomarker disease RGD Identification of differently expressed genes in chemical carcinogen-induced rat bladder cancers. 19399409 2009
Entrez Id: 894
Gene Symbol: CCND2
CCND2
0.200 Biomarker disease RGD Methylation profiling of urothelial carcinoma in bladder biopsy and urine. 17017434 2006
Entrez Id: 9536
Gene Symbol: PTGES
PTGES
0.200 Biomarker disease RGD Elevated prostaglandin E2 level via cPLA2--COX-2--mPGES-1 pathway involved in bladder carcinogenesis induced by terephthalic acid-calculi in Wistar rats. 16621493 2006
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.560 Biomarker disease LHGDN Amplification of CCND1 or alterations in c-myc/CCND1 early in bladder cancer may have clinical relevance in promoting and predicting progression to detrusor-muscle-invasive transitional cell carcinoma. 12237776 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.400 PosttranslationalModification disease LHGDN This prompted our investigation to explore the global Alu methylation and the promoter methylation of the novel putative tumor suppressor genes caveolin-1 and hDAB2IP, and of p53 in transitional cell carcinomas (TCC), squamous cell carcinomas and undifferentiated small cell carcinomas of the urinary bladder. 16328005 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.400 GeneticVariation disease LHGDN Despite the observation that the alterations of p53 gene are associated features of aggressive phenotype of transitional cell carcinomas they do not seem to offer additional prognostic information. 12725329 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.400 AlteredExpression disease LHGDN To evaluate the expression profile of vascular endothelial growth factor (VEGF), kinase-insert-domain-containing receptor (KDR) and p53 in patients from Northeastern China with transitional cell carcinoma (TCC) of bladder. 18645275 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.400 Biomarker disease LHGDN To investigate the prognostic and predictive relevance of p53 protein, Ki-67 antigen, MMP-2 and MMP-9 in patients with transitional cell carcinoma (TCC) of the upper urinary tract. 16351648 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.400 GeneticVariation disease LHGDN We studied whether p53 status has any predictive value on the outcome of intravesical adriamycin (ADR) instillation for superficial transitional cell carcinoma (TCC) of the bladder. 12926093 2003
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.310 AlteredExpression disease LHGDN We investigated uPA and uPAR gene expression in 20 human transitional cell carcinomas (TCC) of the bladder (n=19) and the renal pelvis (n=1) in comparison with adjacent non-malignant tissues. 15375521 2004
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
0.210 AlteredExpression disease LHGDN Overexpression of annexin a1 induced by terephthalic acid calculi in rat bladder cancer. 17994624 2007
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 AlteredExpression disease LHGDN Incidence of Bcl-2 expression in bladder cancer: relation to schistosomiasis. 15329319 2004
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 AlteredExpression disease LHGDN In this study, 47 cases of transitional cell carcinomas (TCCs) were immunohistochemically studied for bcl-2 and bcl-6 protein expression. 12879322 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 AlteredExpression disease LHGDN Identification of patients with transitional cell carcinoma of the bladder overexpressing ErbB2, ErbB3, or specific ErbB4 isoforms: real-time reverse transcription-PCR analysis in estimation of ErbB receptor status from cancer patients. 14614020 2003
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease LHGDN We investigated expression patterns of CD44s and CD44v6 in transitional cell carcinoma (TCC) of the urinary bladder in relation to tumour grade, proliferative activity, and immunoreactivity for p53. 18092951 2007
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 AlteredExpression disease LHGDN Differential C-erbB-2 and VEGF expression following BCG immunotherapy in superficial papillary transitional cell carcinoma of the bladder. 12474525 2002
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease LHGDN Differential expression of CD44 variant isoforms by cell lines and tissue specimens of transitional cell carcinomas. 14981907 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 AlteredExpression disease LHGDN The aim of this study was to evaluate the relationship between HER-2/neu oncogene expression and grade of transitional cell carcinoma (TCC) of the bladder. 17987577 2007
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 AlteredExpression disease LHGDN HER2/neu overexpression in the development of muscle-invasive transitional cell carcinoma of the bladder. 14520464 2003
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 AlteredExpression disease LHGDN To evaluate the expression profile of vascular endothelial growth factor (VEGF), kinase-insert-domain-containing receptor (KDR) and p53 in patients from Northeastern China with transitional cell carcinoma (TCC) of bladder. 18645275 2008
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 AlteredExpression disease LHGDN We examined expression of BCL2 and P53 by immunohistochemical analysis using archival tissue samples taken from patients included in the phase I/II trial of synchronous chemoradiotherapy for advanced transitional cell carcinoma (TCC) of the bladder. 12684626 2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 GeneticVariation disease LHGDN [The mechanism of p16 gene inactivation in human bladder transitional cell carcinoma]. 11869511 1999